one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity connected with bortezomib, a proteasome inhibitor Employed in the remedy of a number of myeloma. Its synthesis or examine is vital for ensuring the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor during the synthesis of abiraterone acetate, a drug Employed in the cure of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound within the synthesis of imatinib, a drug that targets specific sorts of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates during the synthesis of gemcitabine, an anti-most cancers drug. Their analyze is important for optimizing the generation procedure and guaranteeing high purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is made use of to treat breast cancer, and these intermediates are associated with its manufacturing.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the treatment method of breast most cancers. Numerous intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug effective in treating cancers including ovarian, breast, and Androsta-5 lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the procedure of colorectal cancer and tiny cell lung cancer.
three-Amino-one-hydroxyadamantane (CAS 702-82-9): This compound is involved in the synthesis of adamantane derivatives, which have numerous apps, which include antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for type 2 diabetic issues that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the 5'-dibenzoate synthesis of varied gluconic acid derivatives, which happen to be Employed in foods, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor from the synthesis of canagliflozin, a medication made use of to deal with style two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).